Awaiting tests

Chameleon fields: awaiting surprises for tests of gravity in space.

We present a novel scenario where a scalar field acquires a mass which depends on the local matter density: the field is massive on Earth, where the density is high, but is essentially free in the solar system, where the density is low. All existing tests of gravity are satisfied. We predict that near-future satellite experiments could measure an effective Newton's constant in space different f...

Alarmins: awaiting a clinical response.

Alarmins are endogenous molecules that are constitutively available and released upon tissue damage and activate the immune system. Current evidence indicates that uncontrolled and excessive release of alarmins contributes to the dysregulated processes seen in many inflammatory and autoimmune conditions, as well as tumorigenesis and cancer spread. Conversely, alarmins have also been found to pl...

Allophenic mice: a pillar awaiting its superstructure.

Psychological distress in patients awaiting heart transplantation.

Heart transplantation has become an established procedure for the treatment of terminal heart failure. However, due to a shortage of donor organs, the waiting period for a donor organ is increasing. Cross-sectional and retrospective studies have indicated that there is tremendous psychological distress during this waiting period. The aim of this study was to assess this phase systematically and...

Awaiting a new era of cancer immunotherapy.

A major challenge in cancer therapy is the lack of specificity for cancer cells. Antibody-based therapies have better specificity and, thus, improved efficacy over standard chemotherapy regimens. Monoclonal antibodies (mAb) constitute the most rapidly growing class of human therapeutics and are proven agents for recognizing and destroying malignant cells. However, the development of antibody th...